Rome: Centro Storico

Don't be afraid to go to a foreign pharmacy. I forgot to pack my prescription medication on a recent trip to France. When my problem acted up, I went to a local pharmacy. (Look for the green cross.) The pharmacist provided my medication without a prescription and at a fraction of what it would have cost in the United States. In fact, one could benefit by stocking up abroad on medications that would normally be acquired at home at a much higher price.

Preserve even the small number of frequent-flier miles you may obtain by making occasional use of a particular carrier; the miles can be worth money. Even if you don't regularly fly on Delta, Northwest, Continental, or several other airlines, sign up for their frequent-flier programs when you book a long or overseas flight. Points.com allows you to redeem miles for magazine subscriptions, music downloads, and other products. You can also use miles to get small discounts on purchases at retailers such as Amazon.com.

If you plan to visit a theme park, always bring a few sandwich-size Ziploc bags. They'll protect your cell phone and wallet when you're riding on flumes and other water attractions.

I find that hotel bathrooms rarely have enough hangers and hooks for clothes and wet towels, so I always bring a few snap-lock suction hooks. (They function better than regular suction hooks because they're more secure and are therefore able to hold heavier items.) It's always nice to have a place to hang a bathrobe.

When you travel to a beach destination, bring your own snorkel gear. We bought snorkels, masks, and fins at home for half-off (at an end-of-summer sale) before a trip to Hawaii. They didn't take up much room in our luggage, and we would have spent as much or more renting the equipment.

Spring skiing often means a wild temperature shift from morning to afternoon. If you want the option of removing outer layers or switching to a lighter ski jacket midday, attach the lift ticket to your clothing with a split-ring key ring. You'll be able to move your ticket as the weather warms up.

Making international calls back to the States can be confusing if you're using a calling card and you're dialing a number by its catchphrase, such as CALL ATT. Obviously, many countries don't have the English alphabet on the telephone keypad. My solution? I create my own small keypads on a computer, print them out, and attach them inside my wallet, to my passport, and to my calling cards.

For fire-safety reasons, cabins don't have their own irons. Don't wait until the last minute to tackle your evening wardrobe. You can find shared irons down the hall in the laundry room, but lines often form before mealtimes. Opt for off-hours (like mornings).

If you're traveling overseas, be sure to check the fine print concerning passports (go online or call the country's embassy). I had three months before my passport expired and found out at the last minute that I needed six months' leeway to enter Tahiti. Luckily, I was able to get a new passport just in time for my vacation.

Before you head to the airport, stop by the front desk of your hotel or cruise ship and ask if they'll print your boarding pass for you. It'll save Internet browsing fees and time at check-in. It's worked for me at several Marriott hotels and on a Celebrity cruise.

If you book a package over the Internet, print out all the details of what's included and take it with you. When a hotel desk clerk in Paris said that the breakfast buffet we had enjoyed for the previous seven mornings was not included in our package, I was able to show him the printouts and prove him wrong. He apologized profusely and wiped the breakfast charges from our bill.

If you don't have enough frequent-flier miles to get to Europe, use your miles to reach a major airport in the United States and then pay for the overseas flight from there. For a trip to Ireland, my husband and I used Delta SkyMiles to get from Cincinnati to New York's JFK airport and from there took Aer Lingus to Ireland. The Aer Lingus internet special was $267 per person. A Delta flight from Cincinnati to Ireland was $1,150 for two. We saved more than $600.

Cold-weather traveling means turning up the thermostat in your hotel room, and along with the artificially warmed air come dry skin and static electricity. Instead of turning on the heat, fill the bathtub with very hot water and leave the bathroom door open. In about an hour, your entire room will be warm and humidified.

Some people think that traveler's checks aren't necessary anymore, but they really can be useful in a variety of situations. My ATM card wouldn't work on Easter Island, where most restaurants did not accept credit cards and wanted to be paid in pesos. Luckily, our hotel cashed my traveler's checks and gave me the pesos I needed. On Dominica, my purse was stolen. But because I had traveler's checks stashed away in my luggage, the vacation wasn't ruined. I always travel with what I call the "trusty four": American dollars (lots of ones and fives divided up and hidden in several locations), traveler's checks, an ATM card, and a credit card.

I was booking tickets online for an upcoming flight to Europe from the East Coast. One particularly attractive fare was offered on a U.S. airline as well as on its foreign "partner airline." Same plane, same flight, same base price. But it was more than $100 cheaper per ticket to book with the foreign airline versus the U.S.one. We saved more than $400 for four tickets, but we'll be on the same plane!

Baby wipes aren't just for babies. Slip a travel-size pack into your carry-on bag and use the wipes to kill germs on public toilet seats and in phone booths. In a pinch, they can also remove stubborn stains from clothing.

Pay close attention to those newsletters enclosed in your frequent-flier statements. They usually contain special offers and promotions that can earn you double or triple miles if you stay at a certain hotel or eat at a certain restaurant.

Using restaurant.com, you can buy gift certificates good at eateries in your destination city, regularly snagging (in my experience) $25 certificates for as little as $5 to $8.The site is awesome, and it works as well for restaurant certificates in your own city and for obtaining gifts for friends.

When I travel to a new city, I check with the local running club to see if there are any events planned during my stay. The entry fee is usually donated to a charity, and I get great exercise, meet locals, and tour a part of the city I may not have known about.

Travel soap dishes--the colorful plastic ones that have hinged lids--stop small, fragile items from getting damaged or lost in your bags. I can easily label and use them again and again and again.

My husband cut an old contact lens case in two and uses the halves to carry his medication when we're traveling. He prefers them to regular pillboxes because lens cases are watertight and compact enough to carry inside a shirt pocket.

Easily packable, local specialty foods make great gifts for family and friends at home. At the huge Safeway in Kihei, Maui, we found a great selection of chocolate-covered macadamia nuts and Kona coffee beans in elegant gift boxes for far cheaper than in tourist-oriented shops. European grocery stores abound with gift ideas: British teas, French mustards and vinegars, and Italian olive oils are just a few examples. Just bear in mind that meats, produce, and other fresh items are a customs no-no.

If you plan to leave a gratuity for hotel staff, follow our friend Phil's good advice: Give it at the beginning of your vacation, not at the end. He introduces himself to the housekeepers early in the trip and hands them a nice tip. Guess who always has plenty of coffee and fresh towels?

I carry bilingual takeout menus when traveling to countries like China, Korea, and Vietnam. When I'm at a restaurant with no menu (or one that I can't read), I give mine to the waiter so he can point to dishes they can prepare. I've learned to pack a few extra menus, as the restaurants often like to keep a copy.

A small compass is a great travel aid. Aside from the obvious benefits during country drives or hikes, it's extremely helpful in navigating winding city streets and orienting yourself once you exit a subway station.

To save space, pack items for travel that you can use in at least two ways. In a pinch, shampoo can double for detergent when washing your clothes (carry the bottle in a Ziploc bag in your suitcase); sandals or flip-flops also function as slippers; and a swimsuit cover-up can serve as a bathrobe.

Carry a Polaroid camera when traveling to developing countries. In Cambodia, several village children gathered around us, posed enthusiastically for pictures, and were fascinated by their images in our digital camera. We wanted to send them the pictures, but they were unable to tell us their address. Polaroids would have solved the problem!

Before leaving on a trip, I print the names and addresses of my friends and family onto clear mailing labels. (All standard word-processing programs have preset templates for creating address labels.) Then, I take the address-label sheets with me on vacation. Since the addresses are already saved in my computer and the mailing labels are adhesive, addressing postcards has become really easy.

If you go directly from the air-conditioned ship out onto the open-air deck (which is usually warmer and more humid in most cruise destinations), your camera's lens is likely to fog up. Warm the camera with your cabin's hairdryer on a low setting or briefly leave it out on your balcony so it can acclimate to the weather.

Going to a place where you don't speak the language? Take along a picture booklet filled with examples of common food items (chicken, cow, rice, bottled water, coffee, wine, etc.) and use it to find dishes you like—you only have to point to the picture of what you want. We did this during a recent trip to Asia and always had wonderful meals.