Isaac Mizrahi

We rented a car last summer to tour northern Italy. Initially, we contacted Europcar (europcar.com) and got a quote of more than $500. We then clicked on a rental-car link from Best Fares (bestfares.com) and received an offer that knocked off about $50. When we mentioned to Europcar that we'd seen lower offers on the Web, they told us that if we sent them the URL and they could verify the offer, they'd match it. We eventually found a car that was an additional $100 cheaper from a British company. Europcar-which offered better service for our itinerary-accepted that lower price, saving us $150.

When I'm on the road, I often have to use the hotel iron before heading out to business meetings. But getting water into the iron can be a hassle--most irons won't fit under the sink faucet, and using a glass to pour water into the tiny hole is nearly impossible without spilling everywhere. There's an easy solution: Use the carafe from the coffee maker. Just be sure the carafe is clean, or you could end up with coffee stains on your clothes.

We're active travelers but find guided bike tours from companies like Backroads too expensive. Our advice: After rolling into town, ask at a bike shop for the best routes. Better yet, call or e-mail before you leave home (search the Web). We've found group rides and races this way, and have made a lot of friends. We're instant locals!

I try to avoid checking any luggage, but the airlines are getting stricter every day about the size and weight of carry-ons. So when I pack, I put any important stuff in a plastic bag and place it in a front pocket. If I'm told to check my carry-on when I get to the gate, I can just pull out the smaller bag and board.

Instead of packing a complete shaving kit, my husband fills his wide-mouth Nalgene water bottle with items such as razors, spare contact lenses, eyeglasses, toothbrush, and so on. This turned out to be particularly useful on our trip to Costa Rica, where we also took the bottle on our day hikes to volcanoes and the jungle.

For our road trip through the English countryside, I printed out a detailed map for every location we wanted to visit from multimap.com. I labeled each map with the day we planned on using it and wrote down the interesting sites and places to eat along the way. I kept them all in a folder and added brochures from the places we saw. It was a great souvenir upon returning home.

Put your perfume and cologne bottles inside pairs of rolled-up socks to keep them cushioned during your journey.

Put a few plastic trash bags in the outer pockets of your suitcases and carry-ons. If you arrive at your destination and it's raining, you can cover your luggage with the bags while you make your way to your hotel. Just cut a slit for handles or straps.

I unpacked a pair of black slacks recently to find them covered with white fuzz. I didn't have a lint brush handy, so I used the luggage sticker from my bag--the gummy side took the lint right off.

Our bags have been stolen twice from inside locked rental cars. Now we travel with a bicycle cable and lock. If we absolutely have to leave our suitcases in the car, I hook them together by the handles and attach the whole thing to the frame of a seat or a secure item in the trunk. Even if thieves manage to get into our car, the cable will make it very difficult for them to make off with the luggage.

Before you book a room over the phone, peruse the hotel's site for its "Web only" rate. It's often cheaper than the best quote you'll get by calling. Recently, over the phone, I was quoted a daily rate of $129. I booked the same room online for $89.

If you don't have enough frequent-flier miles to get to Europe, use your miles to reach a major airport in the United States and then pay for the overseas flight from there. For a trip to Ireland, my husband and I used Delta SkyMiles to get from Cincinnati to New York's JFK airport and from there took Aer Lingus to Ireland. The Aer Lingus internet special was $267 per person. A Delta flight from Cincinnati to Ireland was $1,150 for two. We saved more than $600.

Certified scuba divers who take prescription medications should keep a doctor's permission-to-dive statement with their certification cards. On a recent trip to Jamaica, I truthfully completed a lengthy questionnaire about my health, revealing that I have medically controlled high blood pressure and cholesterol. I was told I could not dive without a doctor's OK, even though I exercise regularly, am very fit, and have no other health issues. I now carry a letter from my doctor attesting to my fitness for scuba diving.

I teach a Tulane University seminar on independent European travel for first-timers. Until recently, I advocated Europe's great rail networks as the way to go. Now, with the plethora of budget airlines, I recommend a combination of the two. But it makes the planning stage—which I find almost as much fun as actually taking the trip—more involved. Thank goodness for whichbudget.com, a Web site that lists, by city, which budget airlines serve which cities. Then, to find links to all of Europe's state railway Web sites, visit railfaneurope.net. Each site generally features a travel planner and, almost invariably, an English-language option.

Bring a single-hole punch and lanyard on your next cruise. Once aboard, you can make a hole in your plastic key card and attach the lanyard, allowing you to carry the key around your neck. This is especially useful when your dress or slacks have no pockets. Just be sure to put the hole where it won't interfere with the card's magnetic strip.

When my husband and I travel, we take at least three different credit cards. I carry one he doesn't have, he carries one I don't have, and we both bring our primary card. If one of us has our wallet stolen, we can cancel two cards and still have one to use. We each have different ATM cards, too--useful if a machine doesn't honor one of the cards, or if we need more cash than our daily limit allows.

Before leaving on a trip, I print the names and addresses of my friends and family onto clear mailing labels. (All standard word-processing programs have preset templates for creating address labels.) Then, I take the address-label sheets with me on vacation. Since the addresses are already saved in my computer and the mailing labels are adhesive, addressing postcards has become really easy.

After I fell into a stream in Cambodia, my digital camera wouldn't work. Someone suggested leaving the camera in a bag of rice overnight to draw out any condensation. By the next morning, it was dry and working perfectly.

Easily packable, local specialty foods make great gifts for family and friends at home. At the huge Safeway in Kihei, Maui, we found a great selection of chocolate-covered macadamia nuts and Kona coffee beans in elegant gift boxes for far cheaper than in tourist-oriented shops. European grocery stores abound with gift ideas: British teas, French mustards and vinegars, and Italian olive oils are just a few examples. Just bear in mind that meats, produce, and other fresh items are a customs no-no.

I've created files--some general (Southeast Asia), some specific (Hawaii)--for articles and clippings about places I'd like to visit in the future. I don't want all the good tips, restaurant recommendations, and out-of-the-ordinary itineraries to go to waste just because I'm not planning an immediate trip. The files don't have to be super organized--just throw in the clippings, and you can weed through them later. You'll be glad you have the information when you do get a chance to go away.

Always carry peanut butter. A plastic jar is easy to pack, doesn't need refrigeration, is a great source of protein, and makes a quick, cheap meal when coupled with local bread. (But don't forget to pack a plastic knife for spreading it.)

I always pack a Petzl Tikka Plus headlamp. It's small, weighs next to nothing, and is perfect for reading in bed at night without disturbing my husband. They're sold online and at outdoor-gear stores for about $33.

In areas where the majority of people don't speak English, head to an Internet café. In our experience, they're full of friendly young people anxious to practice their English.

When you travel to a beach destination, bring your own snorkel gear. We bought snorkels, masks, and fins at home for half-off (at an end-of-summer sale) before a trip to Hawaii. They didn't take up much room in our luggage, and we would have spent as much or more renting the equipment.

Check out grocery stores in Europe for bargains on wine. On our last trip to Italy, I found a 1993 Banfi Brunello in a small market for $16. If I could find it at all in my local wine shop, that same bottle would cost more than $100. I only wish I had listened to my husband and bought all three of the bottles the store had.

Once the hotel shampoo bottles I always seem to bring home are empty, I refill them with my own brand of shampoo, conditioner, and shower gel--instead of buying travel-size containers at the drugstore. I toss them, along with other small items (toothbrush, toothpaste, nail file, pillboxes, and a comb), into a medium-size Ziploc bag, and I'm ready to go; the clear plastic lets me find things easily.

If you start to feel a painful blister coming on, put some lip balm or Vaseline on the hot spot--it'll help stop the rubbing.

Save major bucks by going onto eBay and purchasing coupons and gift certificates that others don't want or can't use for lodging, transportation, food, and admissions. I've found great discounts for airline and Amtrak tickets; car rentals; entrance to amusement parks such as SeaWorld, Disney, or Universal Studios; as well as overnights at many hotels. For example, I bought a $30 savings coupon at SeaWorld for only $1. Simply search for your destination and then type in "coupon" or "gift certificate."

Ever since my children were small, I've carried recent, wallet-size pictures of them when we all go on vacation, in case we get separated. Now that they are teenagers and traveling with friends' families, too, I send pictures for the other family to bring along with them. I also write my telephone numbers on the back of the pictures so they know where to reach me in an emergency.

Before traveling overseas, look at your health insurance card. If it only shows an 800 or 888 number for precertification of hospital admissions, call that number and obtain the local number with an area code. Many 800 numbers can't be dialed from foreign countries. I learned this the hard way during an emergency hospital admission in Switzerland. The delay in reaching my carrier could have been avoided.