Breaux Bridge (; French: Pont-Breaux; Cajun French: Pont-(de)-Breaux pronounced [pɔ̃ndbʁo]) is a small city in St. Martin Parish, Louisiana, United States. The population is 8,139 as of the 2010 census, up from 7,281 in 2000. It is part of the Lafayette Metropolitan Statistical Area. Originally dubbed "La Capitale Mondiale de l’Écrevisse," Breaux Bridge was officially designated the Crawfish Capital of the World by former Speaker of the Louisiana House of Representatives Bob Angelle. Breaux Bridge hosts an annual Crawfish Festival, and is regionally noted for listing nicknames in its telephone directory.

Lafayette (, French: [lafajɛt]) is a city in the U.S. state of Louisiana. The city is the most populous and parish seat of Lafayette Parish, and is located along the Vermilion River. It is Louisiana's fourth largest incorporated municipality by population and the 234th-most populous in the United States, with a 2020 census population of 121,374; the consolidated city–parish's population was 244,390 in 2019. The Lafayette metropolitan area was Louisiana's third largest metropolitan statistical area with a population of 489,759 at the 2020 population estimates program, overtaking the Shreveport–Bossier City metropolitan area in 2015.Originally established as Vermilionville in the 1820s and incorporated in 1836, Lafayette developed as an agricultural community until the discovery of oil in the area in the 1940s; since the discovery of oil, the city and parish have had the highest number of workers in the oil and natural gas industry in Louisiana as of 2018. With the establishment of the University of Louisiana System's Lafayette campus, and the diversification of its economy, Lafayette and its metropolitan area have experienced population growth and became nicknamed "The Hub City". Culturally, the city and parish of Lafayette are also known as the "Heart of Acadiana".The city, metropolitan area and Acadiana region are major centers for the technology industry, and home to the University of Louisiana at Lafayette, the second largest public research university in Louisiana. Lafayette is also a major center for health care and social services, aerospace, banking and retail. Notable corporations with headquarters or a large presence in the Lafayette area include the Ochsner Health System, IberiaBank, Rouses Market, Petroleum Helicopters International, Amazon, Brookshire Grocery Company, JP Morgan Chase, Albertsons, Perficient, and CGI. The Lafayette area is home to a diverse population from Louisiana Creole and Cajun backgrounds, and was named the "Happiest City in America" in 2014.

Baton Rouge ( BAT-ən ROOZH; from French Bâton-Rouge 'red stick') is the capital city of the U.S. state of Louisiana. On the eastern bank of the Mississippi River, it is the parish seat of East Baton Rouge Parish, the most-populous parish in Louisiana. Since 2020, the city of Baton Rouge has been the 99th-most-populous city in the United States, and second-largest city in Louisiana after New Orleans. It is also the 18th-most-populous state capital. At the U.S. Census Bureau's 2020 tabulation, Baton Rouge had a population of 227,470; the consolidated population of Baton Rouge was 456,781 in 2020 The city of Baton Rouge is the center of the Greater Baton Rouge area, the second-largest metropolitan area in Louisiana, with a population of 870,569 as of 2020, up from 802,484 in 2010.The Baton Rouge area owes its historical importance to its strategic site upon the Istrouma Bluff, the first natural bluff upriver from the Mississippi River Delta at the Gulf of Mexico. This allowed development of a business quarter safe from seasonal flooding. In addition, the city built a levee system stretching from the bluff southward to protect the riverfront and low-lying agricultural areas. The city is a culturally rich center, with settlement by immigrants from numerous European nations and African peoples brought to North America as slaves or indentured servants. It was ruled by seven different governments: French, British, and Spanish in the colonial era; the Republic of West Florida, as a United States territory and state, Confederate, and United States again since the end of the American Civil War. The city of Baton Rouge is a major industrial, petrochemical, medical, research, motion picture, and growing technology center of the American South. It is the location of Louisiana State University, the LSU System's flagship university and the largest institution of higher education in the state. It is also the location of Southern University, the flagship institution of the Southern University System, the only historically black college system in the United States. The Port of Greater Baton Rouge is the 10th-largest in the U.S. in terms of tonnage shipped, and is the farthest upstream Mississippi River port capable of handling Panamax ships. Major corporations participating in the economy of Baton Rouge and its metropolitan statistical area include Lamar Advertising Company, BBQGuys, Marucci Sports, Piccadilly Restaurants, Raising Cane's Chicken Fingers, ExxonMobil, and Dow Chemical Company.

St. Landry Parish (French: Paroisse de Saint-Landry) is a parish located in the U.S. state of Louisiana. As of the 2010 census, the population was 83,384. The parish seat is Opelousas. The parish was created in 1807.St. Landry Parish comprises the Opelousas, LA Micropolitan Statistical Area, which is also included in the Lafayette-Opelousas-Morgan City, LA Combined Statistical Area. It is at the heart of Creole and Cajun culture and heritage in Louisiana.