Wilkesboro is a town in and the county seat of Wilkes County, North Carolina. The population was 3,687 at the 2020 census. The town is located along the south bank of the Yadkin River, directly opposite the town of North Wilkesboro. Wilkesboro is a Small Town Main Street community and has recently revitalized its historic downtown to include the Carolina West Wireless Community Commons, Wilkes Communications Pavilion, Heritage Square and Splash Pad. Cub Creek Park is adjacent to the downtown and contains many amenities to include baseball, walking trails, mountain biking trails, trout fishing, dog park, basketball, tennis, and pickleball courts, picnic shelters, etc. Wilkesboro is also the home of the annual MerleFest, Carolina in the Fall, and Brushy Mountain Peach & Heritage festivals.

Alexander County is a county established in the U.S. state of North Carolina in 1847. As of the 2010 census, the population was 37,198. Its county seat is Taylorsville. Alexander County is part of the Hickory–Lenoir–Morganton, NC Metropolitan Statistical Area.

Alleghany County () is a county located in the U.S. state of North Carolina. As of the 2010 census, the population was 11,155. Its county seat is Sparta.

Elkin is a town in Surry and Wilkes counties in the U.S. state of North Carolina, along the Yadkin River. Elkin shares its name with the surrounding township of Elkin Township. The population was 4,001 at the 2010 census.