Medicine Park is a town in Comanche County, Oklahoma, United States, situated in the Wichita Mountains near the entrance to the 60,000-acre (240 km2) Wichita Mountain Wildlife Refuge. Medicine Park has a long history as a vintage cobblestone resort town. Medicine Park is located near the city of Lawton and Fort Sill. It is an exurb, part of the Lawton Metropolitan Statistical Area. Many of the original structures are constructed of naturally formed cobblestones—these red granite cobblestones are unique to the Wichita Mountains. The population was 382 at the 2010 census.

Woodward is a city in and the county seat of Woodward County, Oklahoma, United States. It is the largest city in a nine-county area. The population was 11,975 at the United States Census. The area was historically occupied by the Kiowa, Comanche, Cheyenne and Arapaho tribes. European-American settlers established the town in 1887 after construction of the railroad to that point for shipping cattle to markets. The town was on the Great Western Cattle Trail. In the 19th century, it was one of the most important depots in the Oklahoma Territory for shipping cattle to the East. As an important cattle town, it had the rough frontier bawdiness of the time. The United States opened up much of the area to European-American settlement by the Land Run of 1893, and migrants rushed into the area. Boiling Springs State Park, named for its artesian springs that seem to boil, has been established east of the city. Federal dockets were held annually in November through 1948, and sporadically at need after that. In the 1990s, Robert Stack hosted an episode of Unsolved Mysteries filmed at the old Woodward Hospital and local Theater. This episode was about the well known tornado that struck Woodward on April 9, 1947. (Season 6, Episode 1).

Lawton is a city in, and the county seat of, Comanche County, in the U.S. state of Oklahoma. Located in southwestern Oklahoma, approximately 87 mi (140 km) southwest of Oklahoma City, it is the principal city of the Lawton, Oklahoma, metropolitan statistical area. According to the 2010 census, Lawton's population was 96,867, making it the fifth-largest city in the state, and the largest in Western Oklahoma.Developed on former reservation lands of the Kiowa, Comanche, and Apache Indians, Lawton was founded by European Americans on 6 August 1901. It was named after Major General Henry Ware Lawton, who served in the Civil War, where he earned the Medal of Honor, and was killed in action in the Philippine–American War. Lawton's landscape is typical of the Great Plains, with flat topography and gently rolling hills, while the area north of the city is marked by the Wichita Mountains. The city's proximity to the Fort Sill Military Reservation, formerly the base of the Apache territory before statehood, gave Lawton economic and population stability throughout the 20th century.Although Lawton's economy is still largely dependent on Fort Sill, it has grown to encompass manufacturing, higher education, health care, and retail. The city has a council-manager government; the city council members are elected from single-member districts and the mayor is elected at-large. They hire a professional city manager to direct daily operations. Interstate 44 and three major United States highways serve the city, while Lawton-Fort Sill Regional Airport connects Lawton by air. Recreation can be found at the city's many parks, lakes, museums, and festivals. Notable residents of the city include many musical and literary artists, as well as several professional athletes.

El Reno is a city in and county seat of Canadian County, Oklahoma, United States. As of the 2010 census, the city population was 16,729. The city was begun shortly after the 1889 land rush and named for the nearby Fort Reno. It is located in Central Oklahoma, about 25 miles (40 km) west of downtown Oklahoma City.