The city of Hood River is the seat of Hood River County, Oregon, United States. It is a port on the Columbia River, and is named for the nearby Hood River. As of the 2010 census, the city population was 7,167. It is the only city in Oregon where public consumption of alcohol on sidewalks or parks is totally unrestricted.

Portland (, PORT-lənd) is the largest and most populous city in the U.S. state of Oregon and the seat of Multnomah County. It is a major port in the Willamette Valley region of the Pacific Northwest, at the confluence of the Willamette and Columbia rivers in Northwestern Oregon. As of 2020, Portland had a population of 652,503, making it the 25th-most populated city in the United States, the sixth-most populous on the West Coast, and the second-most populous in the Pacific Northwest after Seattle. Approximately 2.5 million people live in the Portland metropolitan statistical area (MSA), making it the 25th most populous in the United States. Its combined statistical area (CSA) ranks 19th-largest with a population of around 3.2 million. Approximately 47% of Oregon's population resides within the Portland metropolitan area.Named after Portland, Maine, the Oregon settlement began to be populated in the 1830s near the end of the Oregon Trail. Its water access provided convenient transportation of goods, and the timber industry was a major force in the city's early economy. At the turn of the 20th century, the city had a reputation as one of the most dangerous port cities in the world, a hub for organized crime and racketeering. After the city's economy experienced an industrial boom during World War II, its hard-edged reputation began to dissipate. Beginning in the 1960s, Portland became noted for its growing progressive political values, earning it a reputation as a bastion of counterculture.The city operates with a commission-based government guided by a mayor and four commissioners as well as Metro, the only directly elected metropolitan planning organization in the United States. Its climate is marked by warm, dry summers and cool, rainy winters. This climate is ideal for growing roses, and Portland has been called the "City of Roses" for over a century.

Tualatin () is a city located primarily in Washington County in the U.S. state of Oregon. A small portion of the city is also located in neighboring Clackamas County. It is a southwestern suburb in the Portland Metropolitan Area that is located south of Tigard. The population was 26,054 at the 2010 census.

Vancouver is a city on the north bank of the Columbia River in the U.S. state of Washington, located in Clark County. Incorporated in 1857, Vancouver had a population of 161,791 as of the 2010 U.S. census, and a population of 186,192 as of the 2020 U.S census, making it the fourth-largest city in Washington state. Vancouver is the county seat of Clark County and forms part of the Portland-Vancouver metropolitan area, the 25th largest metropolitan area in the United States. Originally established in 1825 around Fort Vancouver, a fur-trading outpost, the city is located on the Washington–Oregon border along the Columbia River, directly north of Portland.