Nacogdoches ( NAK-ə-DOH-chis) is a small city in East Texas and the county seat of Nacogdoches County, Texas, United States. The 2010 U.S. Census recorded the city's population at 32,996. Nacogdoches is a sister city of the smaller, similarly named Natchitoches, Louisiana, the third-largest city in the southern Ark-La-Tex. Nacogdoches is the home of Stephen F. Austin State University and Texas's largest azalea garden and the Virginia Ave National Historic District.

Jacksonville is a city located in Cherokee County, Texas, United States. The population was 14,544 at the 2010 census. It is the principal city of the Jacksonville Micropolitan Statistical Area, which includes all of Cherokee County, and part of the larger Tyler–Jacksonville combined statistical area. Jacksonville is located in an area of rolling hills in East Texas, north of the county seat, Rusk, and south of Tyler, in neighboring Smith County, on U.S. Highway 69. The north-south Highway 69 intersects the east–west U.S. Highway 79 adjacent to the city's downtown area. Area production and shipping of tomatoes gained the town the title "Tomato Capital of the World". The impressive red iron ore rock Tomato Bowl, built by Works Progress Administration workers during the Great Depression, is home to the Jacksonville High School "Fightin' Indians" football and soccer teams. Annual events include the "Tops in Texas Rodeo" held in May and the "Tomato Fest" celebration in June.

Henderson is a city and the county seat of Rusk County, Texas, in Northeast Texas. Its population was 13,712 at the 2010 census. Henderson is named for James Pinckney Henderson, the first governor of Texas. The city has functioned as a major crossroads in Northeast Texas over the last two centuries. Several major highways pass through the business district of the town, including U.S. Route 259, Texas State Highway 64, U.S. Route 79, Texas State Highway 43, Texas State Highway 42, and Texas State Highway 64. Annual events in the city of Henderson include the Heritage Syrup Festival in November, celebrating the East Texas tradition of syrup making, and the East Texas Sacred Harp Convention in August featuring shape note music. The city has a vibrant downtown historic district, with many buildings dating to before the American Civil War. The city has 19 historical markers, including homes dating from the 1880s, churches, and colleges. Downtown Henderson is one of the most dramatic and charming downtowns in the East Texas area. Colorful, canvas awnings highlight the ornate buildings that house Henderson's downtown merchants, and offer shade to downtown shoppers visiting the various antiques stores, clothing stores, and restaurants lining the main streets.

Palestine ( PAL-i-steen) is a city in and the county seat of Anderson County in Texas, United States. As of the 2010 census, the city population was 18,712. Palestine was named for Palestine, Illinois, by preacher Daniel Parker. Another source says that it was named by migrant Micham Main for the same hometown.Palestine is a relatively small town located in the Piney Woods, equidistant from the major cities of Dallas, and Houston, Texas, and Shreveport, Louisiana. It is notable for its natural environment, including the dogwood floral blooming season, for having 23 historical sites on the National Register of Historic Places, and as the western terminus of the Texas State Railroad. This steam-and-diesel railroad museum operates tourist trains between Palestine and Rusk.