Salem is an independent city in the U.S. commonwealth of Virginia. As of the 2010 census, the population was 24,802. It is the county seat of Roanoke County, although the two are separate jurisdictions. The Bureau of Economic Analysis combines the city of Salem with Roanoke County, which surrounds both Salem and the neighboring City of Roanoke, for statistical purposes. Salem has its own courthouse and sheriff's office, but shares a jail with Roanoke County, which is located in the Roanoke County Courthouse complex in Salem. The Roanoke County Sheriff's Office and Roanoke County Department of Social Services are also located within Salem, though the county administrative offices are located in unincorporated Cave Spring. Roanoke College is located in the city. Salem is also the home to a minor league baseball team, the Salem Red Sox.

Smith Mountain Lake is a large reservoir in the Roanoke Region of Virginia, United States, located southeast of the City of Roanoke and southwest of Lynchburg. The lake was created in 1963 by the Smith Mountain Dam impounding the Roanoke River. The majority of the south shore of the lake lies in Franklin County while a small portion, including access to the dam, lies in Pittsylvania County. Bedford County makes up the northern half of the lake with the Roanoke River as the dividing line. The lake has become a popular recreation spot and has also experienced significant development in the last decade. It is the largest lake contained entirely within the Commonwealth of Virginia.

Franklin County is located in the Blue Ridge foothills of the U.S. state of Virginia. As of the 2010 census, the population was 56,159. Its county seat is Rocky Mount.Franklin County is part of the Roanoke, VA Metropolitan Statistical Area and is located in the Roanoke Region of Virginia. The Roanoke River forms its northeast boundary with Bedford County.

Bedford is an incorporated town and former independent city located within Bedford County in the U.S. state of Virginia. It serves as the county seat of Bedford County. As of the 2010 census, the population was 6,222. It is part of the Lynchburg Metropolitan Statistical Area. Known as the "place that sells itself," Bedford boasts the Blue Ridge Mountains to the North, Smith Mountain Lake to the South, Lynchburg to the East, and I-81/Roanoke to the West.