Marshall County is a county in the U.S. state of West Virginia. At the 2010 census, the population was 33,107. Its county seat is Moundsville. With its southern border at what would be a continuation of the Mason-Dixon line to the Ohio River, it forms the base of the Northern Panhandle of West Virginia. Marshall County is part of the Wheeling, WV-OH Metropolitan Statistical Area. Marshall County is home to the largest conical burial mound in North America, at Moundsville. Marshall County was formed in 1835 from Ohio County by act of the Virginia Assembly. In 1852, on Christmas Eve, workers completed the Baltimore & Ohio Railroad's connection to the Ohio River at Rosby's Rock in Marshall County. It more recently became home to the New Vrindaban community of Hare Krishnas, and Prabhupada's Palace of Gold.

Wheeling is a city in Ohio and Marshall counties in the U.S. state of West Virginia. Located almost entirely in Ohio County, of which it is the county seat, it lies along the Ohio River in the foothills of the Appalachian Mountains. Wheeling was originally a settlement in the British colony of Virginia, and later the second largest city in the Commonwealth of Virginia. Wheeling was where the creation of West Virginia was planned, and it was the first capital of the new state. Due to its location along major transportation routes, including the Ohio River, National Road, and the B&O Railroad, Wheeling became a manufacturing center in the late nineteenth century. After experiencing the closing of factories and substantial population loss following World War II, Wheeling's major industries now include healthcare, education, law and legal services, entertainment and tourism, and energy. Wheeling is the principal city of the Wheeling, WV-OH Metropolitan Statistical Area. As of the 2010 census, the MSA had a population of 147,950, and the city itself had a population of 28,486. From the acceptance of the new state of West Virginia into the union on June 20, 1863, until the Restored Government of Virginia's move to Alexandria in August of the same year, Wheeling was the state capital of both West Virginia and Virginia.

Greene County is a county in the U.S. state of Pennsylvania. As of the 2010 census, the population was 38,686. Its county seat is Waynesburg. Greene County was created on February 9, 1796, from part of Washington County and named for General Nathanael Greene. Greene County is part of the Pittsburgh media market. It is in the area of southwestern Pennsylvania that was claimed by Virginia, the District of West Augusta.

Washington County is a county in the U.S. state of Pennsylvania. As of the 2010 census, the population was 207,820. Its county seat is Washington.Washington County is part of the Pittsburgh, PA Metropolitan Statistical Area. The county is home to Washington County Airport, three miles (5 km) southwest of Washington.