Sheridan is a city in the U.S. state of Wyoming and the county seat of Sheridan County. The city is located halfway between Yellowstone Park and Mount Rushmore by U.S. Route 14 and 16. It is the principal city of the Sheridan, Wyoming, Micropolitan Statistical Area which encompasses all of Sheridan County. The 2010 census put the city's population at 17,444 and the Sheridan, Wyoming, Micropolitan Statistical Area at 29,116, making it the 421st-most populous micropolitan area in the United States.

Big Horn is an unincorporated community and census-designated place (CDP) in Sheridan County, Wyoming, United States. The population was 198 at the 2000 census and 490 at the 2010 census.

Gillette is a city in and the county seat of Campbell County, Wyoming, United States. The town was founded in 1891 as a major railway town on the Chicago, Burlington and Quincy Railroad. The population was estimated at 32,030 as of July 1, 2019. Gillette's population increased 48% in the ten years after the 2000 census, which counted 19,646 residents after a boom in its local fossil fuel industries.Gillette is centrally located in an area involved with the development of vast quantities of American coal, oil, and coalbed methane gas. The city calls itself the "Energy Capital of the Nation"; Wyoming provides nearly 35% of the nation's coal. However, a decline in coal use in the U.S. has led to a decline in the local economy, leading some local officials to look for other industries or employment opportunities. As a major economic hub for the county, the city is also a regional center for media, education, health, and arts.

Thermopolis is the largest town in Hot Springs County, Wyoming, United States, and also the county seat. As of the 2010 U.S. Census, the town population was 3,009. Thermopolis is Greek for Hot City. It is home to numerous natural hot springs, in which mineral-laden waters are heated by geothermal processes. The town is named for the hot springs located there.The town claims the world's largest mineral hot spring, appropriately named "The Big Spring", as part of Wyoming's Hot Springs State Park. The springs are open to the public for free as part of an 1896 treaty signed with the Shoshone and Arapaho Indian tribes. Dinosaur fossils were found on the Warm Springs Ranch in 1993, and the Wyoming Dinosaur Center was founded soon after.