Try taking just one bag
The ultimate website for packing well is OneBag.com. Created 11 years ago, this site encourages people to travel with only one bag, as its name suggests.
A few years ago, I met OneBag.com's creator, Doug Dyment. He's a technical marketer in San Francisco who uses the site to share his thoughts on the the superiority of traveling light. He's refined his strategies over the years as he's learned from hundreds of fellow travelers who have e-mailed him.
Dyment has a fantastic trick for preventing your clothes from becoming wrinkled. As he says, "The common practice of individually folding items of clothing, then piling them atop one another, is just about the worst thing you can do from a packing perspective." His trick is "bundle wrapping" instead. His explanation is better than any I can give, so I encourage you to visit his site, onebag.com.