Point Pleasant is a city in and the county seat of Mason County, West Virginia, United States, at the confluence of the Ohio and Kanawha Rivers. The population was 4,350 at the 2010 census. It is the principal city of the Point Pleasant, WV-OH Micropolitan Statistical Area.

Morgantown is the county seat of Monongalia County, West Virginia, United States, situated along the Monongahela River. West Virginia University is in the city. The population was 30,712 at the 2020 Census Bureau, making Morgantown the largest city in North-Central West Virginia. The Morgantown metropolitan area has a population of 138,176.

Bridgeport is a city in Harrison County, West Virginia, United States. The population was 8,149 at the 2010 census. The town of Bridgeport had its beginning in pre-American Revolutionary War times. In 1764, John Simpson entered the area and gave his name to Simpson Creek. Bridgeport was chartered in 1816. When the town was incorporated in 1887, it established the office of mayor and town council. The city currently employs a City Manager. Bridgeport is home to Meadowbrook Mall, a 100-store regional shopping complex serving North-Central West Virginia.

Clarksburg is a city in and the county seat of Harrison County, West Virginia, United States, in the north-central region of the state. The population of the city was 16,578 at the 2010 census. It is the principal city of the Clarksburg, WV Micropolitan Statistical Area, which had a population of 89,718 in 2019. Clarksburg was named National Small City of the Year in 2011 by the National League of Cities.