Sioux Falls (; Lakota: Íŋyaŋ Okábleča Otȟúŋwahe; "Stone Shatter City") is the most populous city in the U.S. state of South Dakota and the 131st-most populous city in the United States. It is the county seat of Minnehaha County and also extends into Lincoln County to the south, proximate with the Iowa state line. As of 2020, Sioux Falls had a population of 192,517. The Sioux Falls metro area accounts for more than 30% of the state's entire population. Chartered in 1856 on the banks of the Big Sioux River, the city is situated in the rolling hills at the junction of interstates 29 and 90. According to Best Life magazine, Sioux Falls is the healthiest city in the United States and is often considered one of the healthiest cities in the US by many other organizations.

Brookings is a city in Brookings County, South Dakota, United States. Brookings is the fourth largest city in South Dakota, with a population of 22,056 at the 2010 census. It is the county seat of Brookings County, and home to South Dakota State University, the largest institution of higher education in the state. Also found in Brookings are the South Dakota Art Museum, the Children's Museum of South Dakota, the annual Brookings Summer Arts Festival, and the headquarters of a number of manufacturing companies and agricultural operations.

Marshall is a city in Lyon County, Minnesota, United States. The population was 13,680 at the 2010 census. Marshall is a regional center in southwest Minnesota, and the county seat of Lyon County. It is the headquarters of the Schwan Food Company and the home of Southwest Minnesota State University.

Le Mars is the county seat of Plymouth County, Iowa, United States. It is located on the Floyd River northeast of Sioux City. The population was 10,571 at the time of the 2020 census. Le Mars is part of the Sioux City metropolitan area.